Oxidation of allylic and benzylic alcohols to aldehydes and carboxylic acids.
نویسندگان
چکیده
An oxidation of allylic and benzylic alcohols to the corresponding carboxylic acids is effected by merging a Cu-catalyzed oxidation using O2 as a terminal oxidant with a subsequent chlorite oxidation (Lindgren oxidation). The protocol was optimized to obtain pure products without chromatography or crystallization. Interception at the aldehyde stage allowed for Z/E-isomerization, thus rendering the oxidation stereoconvergent with respect to the configuration of the starting material.
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ورودعنوان ژورنال:
- Chemical communications
دوره 50 39 شماره
صفحات -
تاریخ انتشار 2014